Common Side Effects Most side effects are temporary and mild
The triple agonist mechanism appears to match or slightly exceed tirzepatide for blood sugar management , likely because the glucagon component, while it can raise blood sugar in isolation, works synergistically with GLP-1 and GIP activation to produce a net positive effect on glucose regulation
A., Gaskell, H., McIntyre, M., & Wiffen, P
British heart journal , 66 (1), 114
To minimise GLP-1 side effects, these medications are typically prescribed with a process called dose titration starting at a very low dose and gradually increasing it over several weeks to give your body time to adapt
Ethics declarations Conflict of interest The authors indicate no potential conflicts of interest