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one vial covers about 7-15 days
In 2020, combined DRP-104 with atezolizumab (anti-PD-1) entered the clinical trial (NCT04471415) in the treatment of advanced solid tumors (Johnson et al., 2021)
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Further, galectin-1 upregulation aggravates the decreased sensitivity of HCC cells to sorafenib-induced ferroptosis by reducing lipid peroxidation