In a detailed follow-up analysis of SELECT, researchers found: People got similar cardiovascular protection whether they: lost 5% of body weight, or lost very little weight (or even none) Thats a major finding because it suggests semaglutide may protect the heart through multiple pathways, such as: lowering inflammation improving blood vessel function reducing blood pressure improving cholesterol and lipid markers In SELECT, semaglutide also improved several risk indicators, including lower blood pressure and a major drop in C-reactive protein (CRP) a marker linked with inflammation and heart risk
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May 31 2019;55(6)doi:10.3390/medicina55060233
"That is very different from a drug actually causing a new cancer." The review emphasizes that for patients with papillary, follicular, or Oncocytic (Hrthle cell) thyroid cancers, current evidence does not support the idea that GLP-1 medications cause these diseases or worsen their course
Research shows that females are potentially more susceptible to T2D with chronic refined carbohydrate intake, whereas males may be more susceptible to chronic disease when chronically consuming high-fat diets, particularly those high in animal products [121, 122]
Despite SNPs in genes functionally related to taste buds, also genetic variations in other genes have been shown to affect the taste perception and are likewise correlated with parameters of obesity