Recent research suggests that modulating autophagic flux could be a potential therapeutic strategy for various cardiovascular conditions, including atherosclerosis, coronary artery disease, diabetic cardiomyopathy, arrhythmia, chemotherapy-induced cardiotoxicity, and heart failure [106]
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10.1016/j.dmpk.2015.02.003 98 ShiresT
Autonomic dysfunction in long COVID: rationale, physiology and management strategies
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28 For example, p70S6K1 phosphorylates MDM2 at Ser166 resulting in polyubiquitination and degradation of p53 and thereby inhibits p53-dependent apoptosis