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Semaglutide (Ozempic, Wegovy) achieves this through a fatty acid chain that binds to albumin in the blood, shielding it from DPP-4, plus an amino acid substitution that further resists breakdown
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Neurochem Int 62(5):712718 Murnyi M, Lacza Z (2006) Influence of diabetes mellitus on cerebral ischemia and reperfusion injury
Clinical oversight matters because GLP-1 agonists require dose adjustments
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