Nicotinamide N-methyltransferase (NNMT) inhibition increases energy expenditure and decreases fat storage, two important aspects of treating insulin resistance, a defining feature of type 2 diabetes
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doi: 10.1016/j.neuroimage.2016.07.056, 39 SatohT.YoshiokaY
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Of the preclinical studies examined, 22 showed a reduction in amyloid-beta plaques, and 19 showed a reduction in tau tangles