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To date, enough evidence has been generated to support the protective role of these compounds (see Figure 3 ) in models of fibrosis and other fibroblast-mediated conditions, resulting so far in the approval of a clinical trial testing the efficacy of an MC 1 selective molecule MT-7117 (also known as dersimelagon) for the treatment of diffuse cutaneous systemic sclerosis

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Bioactivity of growth hormone releasing hormone (1-29) analogues after SC injection in man