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In male rats experiencing transient ischemic stroke, UA treatment induced IL-6 expression, upregulated STAT3 and NF-B p65 phosphorylation, induced Socs3 expression, and maintained the ramified morphology of Iba-1-positive microglia in the cerebral cortex, suggesting an anti-inflammatory effect of UA [54]

Glutathione dissolves readily at room temperature to a clear, colorless solution

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Even though fundamental and clinical research on AMS has advanced significantly, numerous scientific issues still need to be resolved

doi:10.1186/s12958-018-0434-y