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According to the data presented at the 2025 European Society for Medical Oncology (ESMO) Congress, JSKN003 demonstrated an objective response rate (ORR) of 68.8% and a mPFS of 11.04 months in 32 patients with HER2-positive advanced colorectal cancer, showing a clear therapeutic advantage over existing therapies
Nature Communications (2025) 8
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These overlapped genes which are co-regulated by GSH, Glu, and wounding or independently regulated by GSH and wounding, Glu and wounding are all mainly involved in plant defense signaling, including plant response to wounding, stress, JA, and biotic stimulus, regulation of cell communication, and innate immune response, suggesting that GSH and Glu are involved in wound-induced plant systemic defense response
10.1016/j.clnu.2015.07.001 37 MolinaJ
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