Likewise, Prx5, the last identified member of the six mammalian Prxs (Van der Eecken et al., 2011), and it has been associated with the protection of mtDNA from oxidative attacks ( 2 O 2 is modest (Zhu et al., 2012)
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Hosios AM, Vander Heiden MG
Although flavonoids contribute to stress protection through antioxidant activity, signaling modulation, and defense functions, their biosynthesis requires substantial investments of adenosine triphosphate (ATP), reducing equivalents, phenylalanine, acetyl-CoA, and malonyl-CoA that could otherwise support primary metabolism, respiration, osmotic adjustment, or reproductive development (Dixon and Paiva, 1995
Mood disturbances including irritability, depression, or unusual anxiety