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Increases in EPI stimulate the adenylate cyclase cascade in target cells (Figure 1) including cellular receptors, G-protein coupled receptors, and protein kinase A

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This leads to an increase in whole body radical burden, and increased oxidative damage to cell membranes

Statistical significance was determined by a two-sided unpaired t-test compared to non-cancer samples ( a , b , c ), or untreated cells ( f )

**This product requires DMSO for reconstitution