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We uncover known pathways, such as DAF-16 in mediating the extended lifespan of the glp-1(-) and fem-3(-) mutants, and also reveal additional insights, including a possible central role of sphingolipid metabolism in the longevity of self-sterile mutants and that masculinized mutants may serve as a useful genetic model for further investigation of mating-induced metabolic reprogramming and premature death (Fig
The second category includes RSL3 and DPI7, which directly inhibit GPX4 activity induce ferroptosis
Published online December 19, 2023
Available at: 55 World Anti-Doping Agency (2024b)
Common side effects include dry mouth, insomnia, and loss of appetite
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