GLP-1s, Alcohol, and Blood Sugar Both GLP-1 medications and alcohol can lower blood sugar
We don't know the exact mechanisms yet of how these medications influence alcohol consumption, but our guess is that GLP-1 drugs can reduce the release of dopamine in the brain's motivation center, making previously rewarding behaviors, like over-drinking, less enjoyable, says Michelle Cardel, Ph.D., M.S., RD, chief nutrition officer at WeightWatchers
The study included 3,533 people with kidney disease and Type 2 diabetes, about half of whom took a weekly injection of semaglutide, and half of whom took a weekly placebo shot
122 Notably, the beneficial effects of liraglutide on tau phosphorylation were not replicated by insulin therapy, suggesting that GLP-1RAs confer neuroprotection via mechanisms distinct from insulin signaling pathways
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GLP-1 agonists do not metabolically promote fat storage or weight gain