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About 90% of patients in both groups were also taking riluzole (an approved ALS therapy sold as Rilutek, Tiglutik, or Exservan) during the study
Over the course of treatment, total drug exposure drives weight loss outcomes, not peak levels or absorption speed from individual injections
Non-deficient patients experience enhanced exercise tolerance and reduced fatigue during caloric restriction
In summary, vitamin B12 is essential for many body functions
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