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Semaglutide is a GLP-1 receptor agonist, a type of medication that mimics the effects of GLP-1

As a result, a meta-analysis of 13 RCTs revealed that GLP-1 RAs, including liraglutide, semaglutide, and dulaglutide, are associated with a 23% increased risk of rapid worsening of diabetic retinopathy in T2DM (OR, 1.23

These may include headache, fatigue, body aches, or a general feeling of malaise

A proof-of-concept study published in 2023 demonstrated an oral delivery system of modified GLP-1 using probiotic bacteria in animal models

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