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Diabetic gastroenteropathy (DGE), a prevalent complication of diabetes, impacts the gastrointestinal (GI) tract from the esophagus to the colon, presenting clinical symptoms including esophageal motility disorders, gastroparesis, constipation, diarrhea, and fecal incontinence
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This included circumvention of the complex downhill syndrome, as well as a sudden decrease of blood supply, decreased NO levels in the inferior caval vein tissue, an immediate heavy loss of endothelial cells from the vascular wall, a lower eNOS production ability (Rangan and Bulkley, 1993
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