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B12 injections are generally well tolerated

For example, too much vitamin B6 may cause severe skin lesions, along with other symptoms like numbness, digestive issues, and poor muscle control, according to Mayo Clinic

Because of its size and location, its often considered one of the most comfortable and effective spots, making it a top choice in a clinical environment to ensure you get the maximum benefit from your treatment

Without that, use is off-label and uncoupled from systematic safety monitoring

In many cases, individuals may transition to a maintenance phase where injections are administered less frequently, such as once every two weeks or once a month

doi: 10.1016/j.pnpbp.2020.110051