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Synthetic TLR4 agonists enhance functional antibodies and CD4+ T-cell responses against the Plasmodium falciparum GMZ2.6C multi-stage vaccine antigen

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Once activated, Akt, one of the main downstream targets of mTORC2 [296], induces inhibitory phosphorylation of the positive regulators of autophagy Beclin-1 [297], forkhead box O3 (FoxO3) [257], and glial fibrillary acidic protein (GFAP) [298]

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