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Though afamelanotide is similar to melanotan, the FDA has not approved it for use as a self-tanner
A randomized multicenter trial enrolled subjects with Fitzpatrick skin phototypes III-VI and 15-50% body surface area involvement
In clinical trial, it produced roughly a 6% reduction in body weight over 68 weeks
Using next-generation RNA-seq sequencing technology, they confirmed that GHK-Cu modulates the expression of 4,231 genes , of which 2,861 are upregulated and 1,370 are downregulated
ArticlePubMedPMC 72
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