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Important unresolved questions include whether BPC-157 reaches relevant central compartments under specific experimental conditions, whether observed CNS model effects depend primarily on vascular preservation, whether neurotransmitter changes are primary or secondary, and whether the brain-gut-axis hypothesis can be separated experimentally from general systemic effects
Artificial light at night is a problem
Metallic taste is commonly associated with a deficiency of vitamin B12, D or zinc
If the label lists ergothioneine, or only two of the three compounds, it is a different product
Additionally, 15 of the included studies focused on B12 supplementation, with a total of 5,191 participants (mean: 346 per study)
