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Numerous studies have demonstrated that for every 10% increase in body mass index (BMI), the risk of developing OSAS increases by nearly six-fold (7, 8)

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No matter what weve done, weve not been able to nail precisely why they are resistant. Unexpected resistance The researchers focused on two variants that disrupt an enzyme called PAM (peptidyl-glycine alpha-amidating monooxygenase), which activates several hormones, including GLP-1

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