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To conclude, in this report we have provided the first, to our knowledge, comprehensive biochemical analysis of a TGR selenoprotein from any organism , showing that it has remarkably wide substrate specificity and may be effectively inhibited by a number of low-molecular-weight compounds

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At present, most of the regulatory strategies for Th17/Treg responses are still in the preclinical stage, and the accurate realization of immune regulation is still a major challenge