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The model describes a positive feedback (more cytotoxicity releases more auto-antigens) and a negative one (cytotoxicity stimulates immunoregulatory T Reg )

Availability of data and materials Data supporting the findings of this study are available from the corresponding author upon reasonable request by a qualified researcher and upon approval by the data-clearing committee of the Medical University Vienna

In the present study, we carried forward these four ACs and tested whether the relationships with depression predicted from genomic data (negative with C2 and C3, and positive with C8 and C10) were expressed in actual phenotypes measured in a large cohort (N ~ 2500) with extensive clinical phenotyping

& Philipson, L

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The primary reported issues are local: pain, redness, swelling, bruising, or, in rare cases, infection at the injection site if sterile technique is not followed