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Unlike traditional peptides, Dihexa is a peptidomimetic, meaning it was designed with non-natural structural elements (hexanoic acid caps on both termini) that confer resistance to enzymatic degradation and enable oral bioavailability

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Its titration schedule is as follows: Week 1 (starting dose) : 0.6 mg per day Week 2: 1.2 mg per day Week 3: 1.8 mg per day Week 4: 2.4 mg per day Week 5 and onwards : 3 mg per day (therapeutic or maintenance dose) Rybelsus (semaglutide) daily oral dosing schedule Rybelsus comes in two formulations: R1 and R2

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