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Journal of Physiology, 110(4), 1223-1229
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Due to its polar nature, carnitine cannot diffuse freely across cell membranes and depends on specific transporters, principally OCTN2 (SLC22A5)a high-affinity (Km 46 mol/L), sodium-dependent transporter highly expressed in the brush border membrane of the renal proximal tubules [73, 74]
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