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Taking berberine alongside metformin, insulin, or sulfonylureas such as gliclazide is not recommended without medical supervision, as the combination may cause additive blood glucose-lowering effects and increase the risk of hypoglycaemia

Measure week 6 against the week-0 baseline

As a result, tirzepatide represents a holistic approach to diabetes management, addressing both the physiological and psychological aspects of living with this chronic condition

CONFLICT OF INTEREST The authors declare that they have no competing interests

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