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Stability issues
J., Kwan, J
Non-reducing versus reducing SDS-PAGE run side by side is the classic and inexpensive approach: correctly folded, intramolecularly bonded protein is more compact and migrates differently under non-reducing conditions, disulfide-linked dimers and higher aggregates appear as bands that collapse to monomer on reduction, and comparing the two lanes tells you something no single-condition method does
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The potential for improved fertility also warrants mention
