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Muscle Integrity Models: In models of muscle-wasting conditions (e.g., dystrophic or disuse models), IGF-1 LR3 is used as a probe to evaluate how enhanced IGF signaling might affect muscle-cell survival, differentiation, and turnover dynamics

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Also, ASNase consumption of Asp and glutamate could be supplemented by SLC1A3, thus eliminating the inhibitory effect of ASNase and promoting tumor development

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