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No causal mechanism has been definitively established, but the FDA added a pancreatitis warning to the semaglutide label based on post-marketing case reports and class-wide precautionary reasoning
Phentermine is sometimes used in combination with or as a precursor to GLP-1 therapy
With Rybelsus, that means insurance will likely cover your Rx if its prescribed for people with type 2 diabetes, but not for non-diabetic people for weight loss (an off-label use)
The practical implication is simple
Has a BMI of 27 or greater as well as a disease related to weight
For a person weighing 220 pounds, that translates to more than 33 pounds lost
