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Stimulation of whole blood cells from SZ patients with selective TLR agonists results in enhanced release of pro-inflammatory cytokines (including IL-1, IL-6, IL-8, and TNF-) (150), further supporting the role of TLRs in regulating neuroinflammation in schizophrenia
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Metal-Mediated Signaling: Delivers bioavailable Cu to copper-dependent enzymes and pathways (e.g., lysyl oxidase family) that participate in cross-linking and tissue architecture
This can sometimes lead to a distinct smell in the bottle or a slight aftertaste
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