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It improves insulin sensitivity. Glucose and insulin measurements changed in diet-induced obese mice
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It acts as a dual agonist at amylin receptors (AMY1R, AMY2R, AMY3R, formed by calcitonin receptor heterodimerized with RAMP1-3) and calcitonin receptors, with structural modifications (e.g., N-terminal fatty acid acylation, proline substitutions) preventing fibril formation, enhancing stability, and enabling once-weekly dosing via albumin binding for prolonged circulation
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Are there any side effects or risks
Welts on the skin, hypersentivity to many foods, itching, sneezing, headaches, intolerance to other substances, can all be clues
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