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Assefa, B., et al., Insulin-Like Growth Factor (IGF) Binding Protein-2, Independently of IGF-1, Induces GLUT-4 Translocation and Glucose Uptake in 3T3-L1 Adipocytes

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In [Th(H 3 BNMe 2 BH 3 ) 4 ] three of the four H 3 BNMe 2 BH 3 bind in \(\kappa\) 4 fashion and one binds \(\kappa\) 3 , giving the fifteen fold coordination

It should be kept away from strong chelators (such as high levels of EDTA and related sequestrants), reducing sugars, thiol-bearing actives, and high concentrations of direct acids (for example ascorbic acid or alpha-hydroxy acids at low pH), all of which can compete for the copper center or disrupt the peptide-metal bond and shift the characteristic blue color toward brown or colorless degradation products