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Recent studies have also been undertaken with garlic bulb, which exhibited a substantial DPP-IV inhibition efficacy (IC50 = 70.88 g/ml), and this was because of the presence of caffeic acid 3-glucoside, malonylgenistin, and calenduloside E which have very high binding energy Table 3 (49)

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Yes, and in practice it often is

However, by reducing the acidity of the gastric lumen, these drugs also inhibit the bodys ability to absorb B12 by preventing its splitting from the carrier protein molecules