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Despite eating a healthy diet and exercising regularly, many people struggle to reach their weight loss goals through lifestyle changes alone

Furthermore, GLP-1 acts on central nervous system receptors in the paraventricular nucleus of the hypothalamus and the central nucleus of the amygdala to promote satiety and reduce food intake (Turton et al 1996) (Fig

Stacks with other treatments

In addition, a history of acute pancreatitis is a relative contraindication [89]

GLP-1 medications were originally developed for type 2 diabetes , but are now also approved for people with obesity or weight-related health conditions

2025;24(2):e16716