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The fall in electron potential energy through this electron transport chain (ETC) is used to pump protons out the mitochondrial matrix to the intermembrane space (IMS)

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2020 (11) CD009178

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Using advanced tracer methodologies, the researchers identified a fascinating metabolic phenomenon they termed "brain glucose steal." Due to systemic mitochondrial impairment, non-brain organs were essentially stealing glucose intended for the central nervous system, starving the brain of energy and driving cognitive dysfunction