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Recently, there have been reports of women who have previously struggled with infertility who were able to conceive after starting treatment with a glucagon-like peptide-1 receptor agonist (GLP-1) medication, such as semaglutide or tirzepatide
PMC7871530
Cardiovascular disease and risk management: standards of care in diabetes2024
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Overall, these differing receptor interaction patterns of GLP-1 and oxyntomodulin were associated with larger conformational dynamics within the oxyntomodulin binding pocket during the course of the MD simulation, with the cavity opening and closing, likely due to the lack of stable interactions within the base of the TMD binding pocket, TM2 and ECL2, coupled with more persistent interactions with the upper regions of TM1 and TM7, relative to GLP-1 (Fig
Mar-Apr 2011;25(2):187-98
