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This could include a slowed heartbeat, ongoing and/or severe nausea, and high blood pressure that causes severe headaches or blurred vision

If you suspect you have experienced a side effect, you can report it to the MHRA via the Yellow Card Scheme at yellowcard.mhra.gov.uk or through the Yellow Card app

Huisamen, B., Genis, A., Marais, E

IL-4 causes a rapid increase in choline import, phosphocholine production, and PC biosynthesis ( Retnla ( SLC4A7 , choline dehydrogenase ( CHDH ), choline kinase alpha ( CHKA ), choline acetyltransferase ( CHAT ), and genes related to acetylcholine (ACh)-dependent signaling such as the muscarinic ( CHRM1 and CHRM5 ) and nicotinic ( CHRNA7 ) ACh receptors ( Figure 3 )

Likewise, once a week administration of efpeglenatide, a long acting GLP-1RA, significantly reduced the body weight in obese patients (172)

GLP-1 medications slow gastric emptying and affect appetite-regulating hormones, which can trigger nausea as a side effect