semaglutide neuroprotection and Alzheimer's: are we seeing signals in the brain biology? Semaglutide is a GLP-1 analog, which means it mimics a hormone involved in metabolism and may also influence inflammation and brain Semaglutide's Alzheimer's Trial Failure: Rethinking

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Graphical abstract Similar content being viewed by others Introduction Sodiumglucose co-transporter 2 inhibitors (SGLT2is) and glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have been shown to reduce the incidence of cardiovascular and kidney disease in people with type 2 diabetes, ostensibly independent of their effects on blood glucose [1, 2]