Disorders of cobalamin (vitamin B12) metabolism: emerging concepts in pathophysiology, diagnosis and treatment
doi: 10.1002/cph4.70129 13 GasoyanH.ButschW
That said: human data remains limited, sample sizes are small, and no studies have directly compared direct glutathione supplementation against precursor approaches on meaningful clinical endpoints
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Riboflavin is needed for conversion of dietary vitamin B6 into its active PLP form, and also has its own neuroprotective properties against excitotoxicity, as well as antioxidant functions (92)
Companies, both established and new, would benefit from recognizing this trend and aligning their innovation pipelines with the needs of this expanding segment of the US adult population