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When eating less, it can be challenging to get all the nutrients your body needs, including: Protein essential for maintaining muscle mass during weight loss Iron necessary for oxygen transport and preventing anaemia Vitamin D important for muscle function and overall wellbeing B vitamins crucial for energy production (note that vitamin B12 deficiency is particularly associated with metformin, which is often taken alongside GLP-1 medications) [2] Dehydration is another frequently overlooked cause

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Famularo G, Tzantzoglou S, Santini G, Trinchieri V, Moretti S, Koverech A, De Simone C

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Given that GLP-1 RAs result in weight loss and the pronounced effects of weight loss on haemodynamic disturbance and cardiac reverse remodelling in obese HF patients, the question is, to what extent is the effect of the drugs related to a direct effect on the cardiovascular system in HF

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According to Lillys TRIUMPH-4 release, the most common adverse events with retatrutide were gastrointestinal: nausea diarrhea constipation vomiting decreased appetite Lilly also reported dysesthesia , an altered skin-sensation signal, in: 8.8% of participants on 9 mg 20.9% of participants on 12 mg compared with 0.7% on placebo Those events were generally mild and rarely led to discontinuation, but they are still notable because dysesthesia did not become a headline feature of the earlier semaglutide narrative

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Also, a nutritional program that takes nutritional effects into account in the management of HT provides additional support to the patient during the treatment process

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