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To establish connection with the NO-system, L-NAME (5.0 mg/kg) (worsening) and L-arginine (200.0 mg/kg) (effective only with blunted NO-synthesis, but not alone) were given intraperitoneally alone or in combination (d-arginine 200.0 mg/kg was not effective, data not shown)

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Shaking can damage the fragile peptide chains through mechanical stress, a process called denaturation

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Minimize vial removal time Each time you remove vial to draw dose: Take out vial Draw dose quickly (1-2 minutes) Return to fridge immediately Don't: Leave vial on counter for 30+ minutes Warm to room temperature before drawing (unnecessary for most peptides) Forget to return to fridge (happens more than you'd think) How to tell if your reconstituted peptides have gone bad Recognition prevents using ineffective or unsafe peptides