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Serious reactions to vitamin B12 are very rare, and most people will never experience them

Growth hormone axis treatments for HIV-associated lipodystrophy: a systematic review of placebo-controlled trials

The need for vitamin B 12 is increased by pregnancy and lactation

Other risk factors include older age and higher melanin levels (darker skin pigment), which can reduce vitamin D production from sunlight

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For some, this may mean integrating supplements or injections into their routine to lose weight and improve health