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It can be observed that proglucagon is not expressed by a single gene, but is embedded in a larger gene, and when this large gene expresses a large peptide chain (called preprohormones), it is then cleaved by specific enzymes and post-translationally modified to finally obtain fragments with different biological activities

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Peptides vs GLP-1: Whats the Difference

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AEEA Spacer System The 8-amino-3,6-dioxaoctanoic acid spacer system provides the necessary flexibility and optimal spacing between the peptide backbone and the fatty acid moiety [16] [12]