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Rats in the DEX group showed a significant increase in tail length (10.60 0.36 m), tail DNA % (13.6%), and tail moment (73.27 1.10), compared to the control group (tail length: 1.60 0.08 m
A growing body of evidence demonstrates that the tumor microenvironment, including cancer-associated fibroblasts (CAFs), can modulate drug sensitivity in tumor cells
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Animal studies show robust activation of STING in heart, brain, and kidney after IR injury, and genetic or pharmacologic inhibition of STING reduces tissue damage and inflammation (46, 47)