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This leads to the downregulation of TFR, HMOX1, ferritin, and 4-hydroxynonenal (4-HNE) levels, thereby inhibiting ferroptosis
Compared to the GLOW peptide stack, KLOW provides additional anti-inflammatory effects due to the inclusion of KPV
The redox potentials of T[SH] 2 (2,242 mV) and GSH (2,230 mV) are very similar, though T[SH] 2 (pKa 7.4) and GSH (pKa 8.7) exhibit dramatic differences in their pKa values (Moutiez et al., 1994)
However, some side effects can be bothersome or ongoing
Zhang Y, Zhang Y, Shi X, Han J, Lin B, Peng W, et al
Gastroenterology 157 , 11091122 (2019)
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