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The benzyl alcohol preservative is generally safe at the tiny doses used for diluting medications in adults, but it poses severe risk to neonates
These polymorphisms are likely to contribute to the difference between individuals in responses to xenobiotics and clearance of oxidative stress products and have been associated with various pathologies such as cancer, and cardiovascular or respiratory diseases [60]
123 showed the difference between pharmacokinetic profiles in premature newborns compared with adults, and despite the small sample size, they concluded that it is possible to obtain and maintain high serum concentrations using a single administration of melatonin repeated every 24/48 h
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