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Often manageable with hydration and fiber

[10] [16] The most frequent side-effects of tirzepatide include nausea, vomiting, diarrhea, decreased appetite, constipation, upper abdominal discomfort, and abdominal pain

Another important consideration is muscle loss

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The following supplements have research showing their effect on mast cell degranulation: Access this content: An active subscription is required to access this content