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The 40-week trial tested three doses of orforglipron3 milligrams, 12 milligrams, and 36 milligramsagainst a placebo in 559 patients with type 2 diabetes

As for complications, women who'd discontinued a GLP-1 prior to pregnancy had a 30% higher risk of developing diabetes while pregnant, a 29% higher risk of blood pressure issues during pregnancy, and a 34% higher risk for preterm delivery, the study found

Avellini L, Silvestrelli M, Gaiti A: Training-induced modifications in some biochemical defences against free radicals in equine erythrocytes

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