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Hu FB, Manson JE, Stampfer MJ, Colditz G, Liu S, Solomon CG, et al
The densities of IPT3 and IPT4 domains of two c-MET molecules were completely unresolved in this cryo-EM map, presumably due to structural flexibility
Kulak MV, Cyr AR, Woodfield GW et al (2013) Transcriptional regulation of the GPX1 gene by TFAP2C and aberrant CpG methylation in human breast cancer
A: Not always
The individual studies, published in Cephalgia in 2010, and the pooled results, published in Headache in 2010, both showed a significant decrease in the number of headache days (per 28 days) with eight to nine fewer headache days at 24 weeks as well as a significant improvement in quality of life in the Botox group
Reasonable candidates include: Mild to moderate IBD as an adjunct (never as sole therapy, always with GI oversight) IBS with a documented inflammatory component Post-infectious gut dysfunction where both tissue damage and persistent low-grade inflammation are present Mixed presentations, heartburn plus intestinal sensitivity plus food reactivity, where the clinical picture suggests multiple mechanisms Where this falls apart is when people treat it as a silver bullet
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