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doi:10.1007/s00431-005-0033-8
It has been shown that roGFP2 is almost fully reduced in intact tissues and that a treatment with the GSH1 inhibitor BSO or the electrophilic xenobiotic 1-chloro-2,4-dinitrobenzene led to fully oxidized state of the biosensor accompanied by decreased fluorescence intensity 52
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If the seal looks tampered with, discard the vial
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